BBDNF - ADRUCIL INJECTION; FLUOROURACIL,USP
- MSDS: BBDNF
- Manufacturer: ADRIA LABORATORIES INC TAYLOR PHARMACAL CO
- Product Name: ADRUCIL INJECTION; FLUOROURACIL,USP
- National Stock Number: 6850-00D000920
Product Identification
Product ID:ADRUCIL INJECTION; FLUOROURACIL,USP
MSDS Date:10/25/1991
FSC:6850
NIIN:00D000920
MSDS Number: BBDNF
Responsible Party
COLUMBUS, OH 43216
US
Emergency Phone: 614-764-8100
Info Phone: 614-761-6206
Preparer: A. DANALS
Cage: 58750
Contractor
Cage: 58750
Ingredients
FLUOROURACIL (SARA 302)
CAS: 51-21-8
RTECS: YR0350000
Fraction By Weight: 5%
Hazards
LD50 LC50 Mixture:UNDETERMINED.
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:THE EFFECTS OF OVEREXPOSURE HAVE NOT
BEEN ESTABLIHED BUT IT'S LIKELY THAT AN EXAGGERATION OF KNOWN TOXIC
EFFECTS MAY OCCUR THE MOST PROMINENT OF WHICH ARE MYELOSUPPRESSIVE
& MUCOUS MEMBRANE TOXICITY. ACUTE:BY INJECTION -NAUSEA, VOMITING,
MYELOSUPPRESSIVE. CHRONIC:UNDETERMINED.
Explanation of Carcinogenicity:PER MSDS:CHEM LISTED AS CARCINOGEN/POT
CARCINOGEN:NTP/IARC/OSHA:NO.
Effects of Overexposure:MYELOSUPPRESSIVE & MUCOUS MEMBRANE TOXICITY.
NAUSEA, VOMITING.
Medical Cond Aggravated by Exposure:UNDETERMINED.
First Aid
First Aid:INHAL:SEEK MED ATTN. EYE:RINSE W/COPIOUS AMTS OF WATER.
IRRIGATE IMMED W/WATER OR SALINE. SKIN:WASH THOROUHGLY W/SOAP/WATER
& RINSE W/COPIOUS AMTS OF WATER. INGEST:SEEK MED ATTN.
Fire Fighting
Flash Point:NA
Autoignition Temp:Autoignition Temp Text:NA
Lower Limits:NA
Upper Limits:NA
Extinguishing Media:NONE SPECIFIED BY MANUFACTURER.
Fire Fighting Procedures:EVACUATE PERSONNEL TO SAFE AREA. FIREFIGHERS
SHOULD USE SELF-CONTAINED BREATHING APPARATUS & PORTECTIVE EQPMT.
Unusual Fire/Explosion Hazard:WHEN HEATED TO DECOMPOSITION MATL EMITS
TOXIC FUMES.
Accidental Release
Spill Release Procedures:DEACTIVATE W/DILUTE BLEACH SOLUITON. RINSE
WELL W/WATER.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.
Handling
Handling and Storage Precautions:ADRUCIL IS POTENT ANTI-CANCER
DRUG.CAUTION IN HDNGL/USE MUST BE EXERCISED. IF ADRUCIL SOLN
CONTACTS SKIN/MUCOUSAE IMMED WASH THOROUHGHLY W/SOAP/WATER.
Other Precautions:STORE 15-30C PROTECT FROM LIGHT. SEE PRODUCT INSERT
FOR FURTHER INFORMATION.
Exposure Controls
Respiratory Protection:NIOSH APPORVED RESPIRATOR FOR TOXIC MISTS OR
AEROSOLS.
Ventilation:LOCAL EXHASUAT/MECHANICAL (GENERAL):ADEQUATE/VERTICAL
LAMINAR FLOW HOOD. HEPA FILGER VENTED TO OUTSIDE AIR.
Protective Gloves:SYNTHETIC OR RUBBER GLOVES.
Eye Protection:SPLASH GOGGLES.
Other Protective Equipment:LONG SLEEVED IMPERMEABLE, DISPOSABLE GOWN
W/ELASTIC CUFFS.
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
MSDS DATED 11-8-85.
Chemical Properties
HCC:N1
Boiling Pt:B.P. Text:SIMILAR H2O
Melt/Freeze Pt:M.P/F.P Text:NP
Decomp Temp:Decomp Text:NP
Spec Gravity:1.0297
pH:NP
Viscosity:NP
Evaporation Rate & Reference:UNDETERMINED
Solubility in Water:MISCIBLE
Appearance and Odor:CLEAR TO FAINTLY YELLOW AQUEOUS YELLOW SOLUTION; NO
ODOR.
Percent Volatiles by Volume:95
Corrosion Rate:NP
Stability
Stability Indicator/Materials to Avoid:YES
UNDETERMINNED.
Stability Condition to Avoid:UNDETERMINED.
Hazardous Decomposition Products:FLUORINE & NXO GASES.
Disposal
Waste Disposal Methods:DEACTIVATED W/DILUTE BLEACH SOLN.DISPOSE OF IN
ACCORDANCE WITH YOUR PROCEDURE FOR HAZ WASTE DISPOSAL TO MEET
LOC/STTE/FED REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.